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Coronary artery disease develops when the major blood vessels ― the coronary arteries ― that supply your heart with blood, oxygen and nutrients become damaged or diseased. Cholesterol-containing depos...

Aortic valve disease is a condition where the valve between the main pumping chamber of your heart and the main artery to your body, the aorta, doesn't work properly. Aortic valve disease may be a con...

Congenital heart disease is one or more problems with the heart's structure that you're born with. Congenital heart disease, also called congenital heart defect, can change the way blood flows through...

Heart failure, sometimes known as congestive heart failure, occurs when your heart muscle doesn't pump blood as well as it should. Certain conditions, such as narrowed arteries or high blood pressure,...

Peripheral artery disease, also called peripheral arterial disease, is a common circulatory problem where narrowed arteries reduce blood flow to your limbs. When you develop peripheral artery disease...

Nonalcoholic fatty liver disease (NAFLD) is a term for a range of liver conditions. As the name implies, the main characteristic of NAFLD is too much fat stored in liver cells. Some individuals with N...

When liver disease progresses to an advanced stage, an excess amount of scar tissue replaces the normal liver tissue. This condition is termed cirrhosis. At this stage, the damage is considered irreve...

Your gallbladder is a small, pear-shaped organ on the right side of your abdomen, just beneath your liver. The gallbladder holds a digestive fluid called bile that's released into your small intestin...

Celiac disease, also called sprue, is an immune reaction to eating gluten — a protein found in wheat, barley and rye. If you have celiac disease, eating gluten triggers an immune response in you...

Diverticula are small, bulging pouches that can form in the lining of your digestive system. They are found most often in the lower part of the large intestine (colon). Diverticula are common, especi...