Static wrinkles are caused by a loss of elasticity and collagen in your skin, or damage caused by the sun or smoking. Your skin becomes thinner and drier, and the silhouette of your face changes with age due to volume loss. Dermal fillers lift the skin, smooth out lines and wrinkles, restore volume loss and give you a fresher appearance. Common fillers including hyaluronic acid (marketed as Juvederm) are particularly suited for fine lines and wrinkles around your mouth. For many people, a combination of Botox and fillers will produce the best results.